relatively speaking

sciencenote:

Most scientists believe that cancer happens when several genes of a particular group of cells become mutated. Some people may have more inherited mutations than others, and even with the same amount of environmental exposure, some people are simply more likely to develop cancer.
The following types of genes contribute to cancer:
Tumor suppressor genes are protective genes. Normally, they suppress (limit) cell growth by monitoring the rate at which cells divide into new cells, repairing mismatched DNA (a cause of mutations), and controlling cell death. When a tumor suppressor gene is mutated (due to heredity or environmental factors), cells continue to grow and can eventually form a tumor. BRCA1, BRCA2, and p53 are examples of tumor suppressor genes. In fact, nearly 50% of all cancers involve a missing or damaged p53 gene.
Oncogenes turn a healthy cell into a cancerous one. HER2/neu and ras are two common oncogenes.
DNA repair genes fix any mistakes made when DNA is replicated (copied). Mistakes that aren’t fixed become mutations, which may eventually lead to cancer, especially if the mutation occurs in a tumor suppressor gene or oncogene.
DNA Repair GenesA third type of gene associated with cancer is the group involved in DNA repair and maintenance of chromosome structure. Environmental factors, such asionizing radiation, UV light, and chemicals, can damage DNA. Errors in DNA replication can also lead to mutations. Certain gene products repair damage to chromosomes, thereby minimizing mutations in the cell. When a DNA repair gene is mutated its product is no longer made, preventing DNA repair and allowing further mutations to accumulate in the cell. These mutations can increase the frequency of cancerous changes in a cell. A defect in a DNA repair gene called XP (Xeroderma pigmentosum) results in individuals who are very sensitive to UV light and have a thousand-fold increase in the incidence of all types of skin cancer. There are seven XP genes, whose products remove DNA damage caused by UV light and other carcinogens. Another example of a disease that is associated with loss of DNA repair is Bloom syndrome, an inherited disorder that leads to increased risk of cancer, lung disease, and diabetes. The mutated gene in Bloom syndrome, BLM, is required for maintaining the stable structure of chromosomes. Individuals with Bloom syndrome have a high frequency of chromosome breaks and interchanges, which can result in the activation of oncogenes. 

sciencenote:

Most scientists believe that cancer happens when several genes of a particular group of cells become mutated. Some people may have more inherited mutations than others, and even with the same amount of environmental exposure, some people are simply more likely to develop cancer.

The following types of genes contribute to cancer:

  • Tumor suppressor genes are protective genes. Normally, they suppress (limit) cell growth by monitoring the rate at which cells divide into new cells, repairing mismatched DNA (a cause of mutations), and controlling cell death. When a tumor suppressor gene is mutated (due to heredity or environmental factors), cells continue to grow and can eventually form a tumor. BRCA1BRCA2, and p53 are examples of tumor suppressor genes. In fact, nearly 50% of all cancers involve a missing or damaged p53 gene.

  • Oncogenes turn a healthy cell into a cancerous one. HER2/neu and ras are two common oncogenes.

  • DNA repair genes fix any mistakes made when DNA is replicated (copied). Mistakes that aren’t fixed become mutations, which may eventually lead to cancer, especially if the mutation occurs in a tumor suppressor gene or oncogene.

DNA Repair Genes
A third type of gene associated with cancer is the group involved in DNA repair and maintenance of chromosome structure. Environmental factors, such asionizing radiation, UV light, and chemicals, can damage DNA. Errors in DNA replication can also lead to mutations. Certain gene products repair damage to chromosomes, thereby minimizing mutations in the cell. When a DNA repair gene is mutated its product is no longer made, preventing DNA repair and allowing further mutations to accumulate in the cell. These mutations can increase the frequency of cancerous changes in a cell. A defect in a DNA repair gene called XP (Xeroderma pigmentosum) results in individuals who are very sensitive to UV light and have a thousand-fold increase in the incidence of all types of skin cancer. There are seven XP genes, whose products remove DNA damage caused by UV light and other carcinogens. Another example of a disease that is associated with loss of DNA repair is Bloom syndrome, an inherited disorder that leads to increased risk of cancer, lung disease, and diabetes. The mutated gene in Bloom syndrome, BLM, is required for maintaining the stable structure of chromosomes. Individuals with Bloom syndrome have a high frequency of chromosome breaks and interchanges, which can result in the activation of oncogenes. 

Knowing

Key to successful living is knowing what you want. 

If you’re like me living without that conviction of knowing what you want then life turns null. You start to live a stale life. 

Immediate goal: Figure out what I want in this life and LIST them.

I need to figure out if I even want to get married. Or be in a relationship. 

Need to have that conviction of knowing that pharmacy IS the right path for me.

Do I want to get skinny or stay average?

Do I want to go to class and succeed or skip and be unsure?

Do I want to be a devout Christian or be a teeter totter.

What type of person do I want to be in public? Smiling? Mean? Mysterious? Witty? Funny? 

**I NEED TO GET MY LIFE STARTED AND IT STARTS BY FIGURING OUT WHAT I WANT! DO IT NOW!!!**

http://www.openbible.info/topics/lukewarm_christians

guts

i wish i had more guts. to tell someone i like them. love them even. not just as friends love but completely infatuated with that person since the 10th grade. i remember the single moment where it hit me soo hard. sitting right across the table from me wearing a black shirt. i had even marked that day in my HS planner.

BUT i’m afraid they’d feel uncomfortable. heck i do too. but i know the chemistry is there. maybe God wants that relationship to blossom later? but i can’t always assume that. i feel that time is ticking. and that person will eventually find another or another will find them. and i will hate myself for a long time. 

i think this sudden urge to put myself out there is because i haven’t felt ‘alive’ alive in so long. i’ve dated all throughout college. but i did it somewhat thoughtlessly. and it’s been almost 2 yrs since i’ve officially dated anyone. that’s a long time. i’ve had flings here and there but most lasted a few days average. i’m at a somewhat safe place right now i guess you could say. but i lost that fire and passion for life. of feeling that passionate love for someone. of wanting to do everything in my power to succeed and do well for that one person. of course there’s family but that’s very different.

i kind of hope that person will come across this one day and know in an instant i’m talking about them. and we can come to a mutual agreement. i’ve been thinking about how things would work for 9 yrs now. so even if it doesn’t work out i’m ready for that. but they should know that i’m there for that person no matter what happens as well. kind of gay saying this but that person is MY soulmate. i may not be their ideal one but it still works for me.

peace.

[Flash 10 is required to watch video]

LOL how the heck did they keep a straight face through this! lolll

(Source: sealedwithakick, via darkanglee)

glee theory #1

glee is my nickname fyi (i was glee before the awesome tv show glee came out).

anyways, as i mentioned in my previous post, it’s in our human nature to adapt and move forward. somewhat evolve. thus my theory on the solution of world overpopulation is… homosexuality. 

i understand those ppl who consider it a perverse immorality and i agree there are those who do take it too far. but there are always going to be a percentage of each group/race/religion etc. that is how should i say… trash? white trash, black trash, asian trash… you know what i’m talking about. basically the ignorant fools that make a certain race or religion look god awful. i know that we are all human and equal in all aspects… but i can’t help but think if we got rid of certain ppl the world would be a better place. horrible thing to say but i can’t help that i feel that way sometimes.

anyways… homosexuality. i hope in the near future the world will become more accepting towards it. i don’t label myself homosexual or heterosexual (another post). but i do believe that we should have the freedom to love whomever. and because of overpopulation the world NEEDS to be more accepting and supportive. i fully support same sex couples adopting and having children. but naturally it’s impossible. and i feel that it does somewhat subside the population epidemic. 

soo yea. just trying to say it’s a WIN WIN scenario. really hope i didn’t offend anyone by this post. 

going to NOVA today to see family! cousins are on some church retreat though. boo. 

pure bliss! could stare at this pic for long periods of time. and the ears! drives me crazy.

pure bliss! could stare at this pic for long periods of time. and the ears! drives me crazy.